164.5K XNAS Volume
XNAS 25 Mar, 2025 2:15 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Lance Kurata | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 60,000 | 60,000 | - | - | Employee Stock Option (right to buy) | |
| Andrew Sassine H. | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 60,000 | 60,000 | - | - | Employee Stock Option (right to buy) | |
| Payne E. Joseph | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 196,000 | 196,000 | - | - | Employee Stock Option (right to buy) | |
| Chivukula Padmanabh | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Dec 2024 | 60,000 | 60,000 | - | - | Employee Stock Option (right to buy) | |
| Chivukula Padmanabh | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 20.76 per share. | 15 Oct 2024 | 12,000 | 435,334 (2%) | 0% | 20.8 | 249,121 | Common Stock |
| M. Slaoui Moncef | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2024 | 14,794 | 14,794 | - | - | Stock option (right to buy) | |
| Slaoui M. Moncef | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 19 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| James F. Barlow | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 13,131 (0%) | 0% | 0 | Common Stock | |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| James F. Barlow | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| Peter C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| Peter C. Farrell | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 55,741 (0%) | 0% | 0 | Common Stock | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| Magda Marquet | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 3,131 (0%) | 0% | 0 | Common Stock | |
| Magda Marquet | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| Edward W. Holmes | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 3,131 (0%) | 0% | 0 | Common Stock | |
| Edward W. Holmes | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| John H. Markels | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 3,131 (0%) | 0% | 0 | Common Stock | |
| John H. Markels | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| John H. Markels | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| Jing L. Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Jun 2024 | 15,000 | 15,000 | - | - | Stock option (right to buy) | |
| Jing L. Marantz | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 3,131 (0%) | 0% | 0 | Common Stock | |
| Jing L. Marantz | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jun 2024 | 3,131 | 0 | - | - | Deferred Stock Units | |
| Andrew H. Sassine | Director, Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 32.03 per share. | 12 Jun 2024 | 50,000 | 220,526 (1%) | 0% | 32.0 | 1,601,500 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 45.00 per share. | 05 Jun 2024 | 114 | 447,334 (2%) | 0% | 45 | 5,130 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 40.01 per share. | 03 Jun 2024 | 26,000 | 447,448 (2%) | 0% | 40.0 | 1,040,234 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 35.02 per share. | 25 Mar 2024 | 17,435 | 473,448 (3%) | 0% | 35.0 | 610,574 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 35.01 per share. | 19 Mar 2024 | 8,565 | 490,883 (3%) | 0% | 35.0 | 299,839 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| H. Andrew Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 75,000 | 75,000 | - | - | Employee Stock Option (right to buy) | |
| Kurata Lance | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 75,000 | 75,000 | - | - | Employee Stock Option (right to buy) | |
| Keith Kummerfeld C. | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 30,000 | 30,000 | - | - | Employee Stock Option (right to buy) | |
| Payne Joseph E. | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Dec 2023 | 200,000 | 200,000 | - | - | Employee Stock Option (right to buy) | |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 17.37 per share. | 15 Aug 2023 | 1,223 | 270,526 (1%) | 0% | 17.4 | 21,248 | Common Stock |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock option (right to buy) | |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock option (right to buy) | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock option (right to buy) | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 34.91 per share. | 01 Aug 2023 | 5,000 | 514,448 (3%) | 0% | 34.9 | 174,550 | Common Stock |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock Option (right to buy) | |
| John H. Markels | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock option (right to buy) | |
| John H. Markels | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Jing L. Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 3,131 | 3,131 | - | - | Deferred Stock Units | |
| Jing L. Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Aug 2023 | 11,869 | 11,869 | - | - | Stock option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 14 Jul 2023 | 6,968 | 950 (0%) | 0% | 35 | 243,880 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.04 per share. | 14 Jul 2023 | 4,500 | 5,450 (0%) | 0% | 9.0 | 40,680 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.99 per share. | 14 Jul 2023 | 1,437 | 6,887 (0%) | 0% | 5.0 | 7,171 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.12 per share. | 14 Jul 2023 | 1,031 | 7,918 (0%) | 0% | 14.1 | 14,558 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jul 2023 | 4,500 | 21,000 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jul 2023 | 1,437 | 7,126 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 14 Jul 2023 | 1,031 | 7,938 | - | - | Employee Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 35.01 per share. | 14 Jul 2023 | 25,000 | 519,448 (3%) | 0% | 35.0 | 875,250 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 28.75 per share. | 03 Jul 2023 | 5,000 | 544,448 (3%) | 0% | 28.8 | 143,750 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 27.16 per share. | 01 Jun 2023 | 5,000 | 549,448 (3%) | 0% | 27.2 | 135,800 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 30.24 per share. | 10 May 2023 | 7,925 | 554,448 (3%) | 0% | 30.2 | 239,652 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 10 May 2023 | 17,075 | 562,373 (3%) | 0% | 30 | 512,250 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 25.93 per share. | 01 May 2023 | 5,000 | 579,448 (3%) | 0% | 25.9 | 129,650 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 14.12 per share. | 17 Apr 2023 | 1,031 | 1,981 (0%) | 0% | 14.1 | 14,558 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 1,437 | 8,563 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 4,500 | 25,500 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Apr 2023 | 1,031 | 8,969 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Sale of securities on an exchange or to another person at price $ 28.18 per share. | 17 Apr 2023 | 6,968 | 950 (0%) | 0% | 28.2 | 196,358 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.99 per share. | 17 Apr 2023 | 1,437 | 7,918 (0%) | 0% | 5.0 | 7,171 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 9.04 per share. | 17 Apr 2023 | 4,500 | 6,481 (0%) | 0% | 9.0 | 40,680 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 25.38 per share. | 03 Apr 2023 | 5,000 | 584,448 (3%) | 0% | 25.4 | 126,900 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 16.07 per share. | 06 Mar 2023 | 5,000 | 589,448 (3%) | 0% | 16.1 | 80,350 | Common Stock |
| Magda Marquet | Director | Purchase of securities on an exchange or from another person at price $ 18.00 per share. | 15 Dec 2022 | 2,222 | 24,942 (0%) | 0% | 18 | 39,996 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Joseph E. Payne | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 250,000 | 250,000 | - | - | Employee Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| Lance Kurata | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Dec 2022 | 125,000 | 125,000 | - | - | Employee Stock Option (right to buy) | |
| John H. Markels | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2022 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| John H. Markels | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Dec 2022 | 6,986 | 6,986 | - | - | Stock option (right to buy) | |
| Joseph E. Payne | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 16.51 per share. | 23 Nov 2022 | 5,000 | 1,480,097 (9%) | 0% | 16.5 | 82,550 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 18.42 per share. | 15 Aug 2022 | 1,068 | 269,303 (1%) | 0% | 18.4 | 19,672 | Common Stock |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Jing Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2022 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2022 | 85,000 | 85,000 | - | - | Employee Stock Option (right to buy) | |
| Joseph E. Payne | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2022 | 150,000 | 150,000 | - | - | Employee Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2022 | 33,000 | 33,000 | - | - | Employee Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2022 | 85,000 | 85,000 | - | - | Employee Stock Option (right to buy) | |
| Lance Kurata | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 21 Jun 2022 | 50,000 | 50,000 | - | - | Employee Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 04 Jan 2022 | 8,100 | 594,448 (3%) | 0% | 40 | 324,000 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 16 Dec 2021 | 3,633 | 602,548 (3%) | 0% | 40.0 | 145,328 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 08 Dec 2021 | 6,367 | 606,181 (4%) | 0% | 40 | 254,680 | Common Stock |
| Jing Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2021 | 20,000 | 20,000 | - | - | Stock option (right to buy) | |
| Jing Marantz | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Dec 2021 | 6,699 | 6,699 | - | - | Stock option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 44.41 per share. | 01 Nov 2021 | 10,000 | 612,548 (4%) | 0% | 44.4 | 444,100 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 44.36 per share. | 01 Sep 2021 | 10,000 | 622,548 (4%) | 0% | 44.4 | 443,600 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 55.86 per share. | 01 Sep 2021 | 10,000 | 632,548 (4%) | 0% | 55.9 | 558,600 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 40.07 per share. | 03 Aug 2021 | 10,000 | 642,548 (4%) | 0% | 40.1 | 400,700 | Common Stock |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2021 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2021 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2021 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Karah Parschauer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2021 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2021 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 42.95 per share. | 01 Apr 2021 | 10,000 | 652,548 (4%) | 0% | 43.0 | 429,500 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 54.23 per share. | 01 Mar 2021 | 10,000 | 662,548 (4%) | 0% | 54.2 | 542,300 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 75.31 per share. | 01 Feb 2021 | 10,000 | 672,548 (4%) | 0% | 75.3 | 753,100 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 46.40 per share. | 04 Jan 2021 | 10,000 | 682,548 (4%) | 0% | 46.4 | 464,000 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Joseph E. Payne | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2020 | 175,000 | 175,000 | - | - | Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2020 | 45,000 | 45,000 | - | - | Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2020 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Lance Kurata | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Dec 2020 | 25,000 | 25,000 | - | - | Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 96.19 per share. | 01 Dec 2020 | 10,000 | 692,548 (4%) | 0% | 96.2 | 961,900 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 55.28 per share. | 02 Nov 2020 | 10,000 | 702,548 (4%) | 0% | 55.3 | 552,800 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 42.83 per share. | 01 Oct 2020 | 10,000 | 712,548 (4%) | 0% | 42.8 | 428,300 | Common Stock |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Sale of securities on an exchange or to another person at price $ 45.16 per share. | 03 Sep 2020 | 10,000 | 722,548 (4%) | 0% | 45.2 | 451,600 | Common Stock |
| Lance Kurata | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Aug 2020 | 90,000 | 90,000 | - | - | Stock Option (right to buy) | |
| James F. Barlow | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Peter C. Farrell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Magda Marquet | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Karah Parschauer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Edward W. Holmes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 22 Jun 2020 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Purchase of securities on an exchange or from another person at price $ 33.33 per share. | 12 Jun 2020 | 450 | 950 (0%) | 0% | 33.3 | 14,999 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 29.74 per share. | 10 Jun 2020 | 5,000 | 273,245 (1%) | 0% | 29.7 | 148,700 | Common Stock |
| Joseph E. Payne | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 31.69 per share. | 10 Jun 2020 | 1,000 | 1,475,097 (9%) | 0% | 31.7 | 31,690 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2020 | 80,000 | 80,000 | - | - | Stock Option (right to buy) | |
| Joseph E. Payne | Director, President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2020 | 100,000 | 100,000 | - | - | Stock Option (right to buy) | |
| Keith C. Kummerfeld | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2020 | 10,000 | 10,000 | - | - | Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Feb 2020 | 60,000 | 60,000 | - | - | Stock Option (right to buy) | |
| Andrew H. Sassine | Director, Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 9.73 per share. | 05 Dec 2019 | 5,649 | 268,245 (1%) | 0% | 9.7 | 54,965 | Common Stock |
| Andrew H. Sassine | Director, Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 10.00 per share. | 03 Dec 2019 | 10,000 | 257,596 (1%) | 0% | 10 | 100,000 | Common Stock |
| James F. Barlow | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Peter C. Farrell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Magda Marquet | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Karah Parschauer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Karah Parschauer | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Edward W. Holmes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 20,000 | 20,000 | - | - | Stock Option (right to buy) | |
| Edward W. Holmes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Oct 2019 | 15,000 | 15,000 | - | - | Stock Option (right to buy) | |
| Magda Marquet | None | Purchase of securities on an exchange or from another person at price $ 10.58 per share. | 13 Sep 2019 | 2,300 | 22,720 (0%) | 0% | 10.6 | 24,334 | Common Stock |
| Keith C. Kummerfeld | See Remarks | Purchase of securities on an exchange or from another person at price $ 10.69 per share. | 12 Sep 2019 | 500 | 500 (0%) | 0% | 10.7 | 5,347 | Common Stock |
| Joseph E. Payne | Director, President and CEO, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 11.22 per share. | 29 Aug 2019 | 5,000 | 1,474,097 (9%) | 0% | 11.2 | 56,100 | Common Stock |
| Andrew H. Sassine | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 10.90 per share. | 23 Aug 2019 | 10,000 | 247,596 (1%) | 0% | 10.9 | 109,000 | Common Stock |
| Peter C. Farrell | None | Purchase of securities on an exchange or from another person at price $ 10.85 per share. | 19 Aug 2019 | 4,432 | 42,955 (0%) | 0% | 10.8 | 48,087 | Common Stock |
| Peter C. Farrell | None | Purchase of securities on an exchange or from another person at price $ 11.02 per share. | 19 Aug 2019 | 4,681 | 38,523 (0%) | 0% | 11.0 | 51,585 | Common Stock |
| Joseph E. Payne | President and CEO, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2019 | 60,000 | 60,000 | - | - | Non-Qualified Stock Option (right to buy) | |
| Keith C. Kummerfeld | Vice President of Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2019 | 10,000 | 10,000 | - | - | Incentive Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2019 | 1,667 | 1,667 | - | - | Incentive Stock Option (right to buy) | |
| Padmanabh Chivukula | Chief Scientific Officer & COO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Feb 2019 | 38,333 | 38,333 | - | - | Non-Qualified Stock Option (right to buy) |